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1

Targeted Cargo Delivery in Senescent Cells Using Capped Mesoporous Silica Nanoparticles

Alessandro Agostini, Dr. Laura Mondragón, Dr. Andrea Bernardos, Prof. Ramón Martínez-Máñez, Dr. M. Dolores Marcos, Dr. Félix Sancenón, Dr. Juan Soto, Prof. Ana Costero, Dr. Cristina Manguan-García, Pr

Journal:

Angewandte Chemie

Year:

2012

Language:

english

File:

PDF, 845 KB

english, 2012

2

A component mode synthesis based hybrid method for the dynamic analysis of complex systems

Roibás Millán, E., Chimeno Manguán, M., Simón Hidalgo, F.

Journal:

Journal of Sound and Vibration

Year:

2015

Language:

english

File:

PDF, 1.21 MB

english, 2015

3

Numerical modelling of structures with thin air layers

Chimeno Manguán, M., Roibás Millán, E., López-Díez, J., Simón, F.

Journal:

Aerospace Science and Technology

Year:

2014

Language:

english

File:

PDF, 874 KB

english, 2014

4

The MEOW lunar project for education and science based on concurrent engineering approach

Roibás-Millán, E., Sorribes-Palmer, F., Chimeno-Manguán, M.

Journal:

Acta Astronautica

Year:

2018

Language:

english

File:

PDF, 1.64 MB

english, 2018

5

On the determination of the modulus of elasticity of plasterboard plates

Chimeno Manguán, M., Roibás Millán, E., Simón Hidalgo, F.

Journal:

Construction and Building Materials

Year:

2018

Language:

english

File:

PDF, 942 KB

english, 2018

6

Dynamic coupling on the design of space structures

García-Pérez, Andrés, Sanz-Andrés, Ángel, Alonso, Gustavo, Chimeno Manguán, Marcos

Journal:

Aerospace Science and Technology

Year:

2018

Language:

english

File:

PDF, 3.13 MB

english, 2018

7

Pyrazino[1,2-b]isoquinolines: Synthesis and study of their cytostatic and cytotoxic properties

Irene Ortín, Juan Francisco González, Elena de la Cuesta, Cristina Manguan-García, Rosario Perona, Carmen Avendaño

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 859 KB

english, 2008

8

Cytotoxicity mechanisms of pyrazino[1,2-b]isoquinoline-4-ones and SAR studies

Irene Ortín, Juan Francisco González, Elena de la Cuesta, Cristina Manguan-García, Rosario Perona, Carmen Avendaño

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 622 KB

english, 2009

9

FK506 sensitizes mammalian cells to high osmolarity by modulating p38 MAP kinase activation

I. Sanchez-Perez, C.J. Rodriguez-Hernandez, C. Manguan-García, A. Torres, R. Perona, J.R. Murguía

Journal:

Cellular and Molecular Life Sciences

Year:

2004

Language:

english

File:

PDF, 314 KB

english, 2004

10

Telomerase deficiency and cancer susceptibility syndromes

Rosario Perona, Rosario Machado-Pinilla, Cristina Manguan, Jaime Carrillo

Journal:

Clinical and Translational Oncology

Year:

2009

Language:

english

File:

PDF, 270 KB

english, 2009

11

IGFBP-3 hypermethylation-derived deficiency mediates cisplatin resistance in non-small-cell lung cancer

Ibanez de Caceres, I, Cortes-Sempere, M, Moratilla, C, Machado-Pinilla, R, Rodriguez-Fanjul, V, Manguán-García, C, Cejas, P, López-Ríos, F, Paz-Ares, L, de CastroCarpeño, J

Journal:

Year:

2009

Language:

english

File:

PDF, 757 KB

english, 2009

12

MKP1/CL100 controls tumor growth and sensitivity to cisplatin in non-small-cell lung cancer

Chattopadhyay, S, Machado-Pinilla, R, Manguan-García, C, Belda-Iniesta, C, Moratilla, C, Cejas, P, Fresno-Vara, J A, de Castro-Carpeño, J, Casado, E, Nistal, M

Journal:

Year:

2006

Language:

english

File:

PDF, 278 KB

english, 2006

13

Targeted Cargo Delivery in Senescent Cells Using Capped Mesoporous Silica Nanoparticles

Alessandro Agostini, Dr. Laura Mondragón, Dr. Andrea Bernardos, Prof. Ramón Martínez-Máñez, Dr. M. Dolores Marcos, Dr. Félix Sancenón, Dr. Juan Soto, Prof. Ana Costero, Dr. Cristina Manguan-García, Pr

Journal:

Angewandte Chemie International Edition

Year:

2012

Language:

english

File:

PDF, 1010 KB

english, 2012

14

Checkpoint kinase 1 modulates sensitivity to cisplatin after spindle checkpoint activation in SW620 cells

A. Peralta-Sastre, C. Manguan-Garcia, A. de Luis, C. Belda-Iniesta, S. Moreno, R. Perona, I. Sanchez-Perez

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2010

Language:

english

File:

PDF, 1.17 MB

english, 2010

15

hCCR4/cNOT6 targets DNA-damage response proteins

I. Sanchez-Perez, C. Manguan-Garcia, M. Menacho-Marquez, J.R. Murguía, R. Perona

Journal:

Year:

2009

Language:

english

File:

PDF, 780 KB

english, 2009

16

MKP1 repression is required for the chemosensitizing effects of NF-κB and PI3K inhibitors to cisplatin in non-small cell lung cancer

María Cortes-Sempere, Sharmila Chattopadhyay, Ana Rovira, Vanessa Rodriguez-Fanjul, Cristobal Belda-Iniesta, Marian Tapia, Paloma Cejas, Rosario Machado-Pinilla, Cristina Manguan-García, Isabel Sánche

Journal:

Year:

2009

Language:

english

File:

PDF, 1.23 MB

english, 2009

17

P-103 Role of JNK/MKP1 and PI3K/NF B on response of non-small cell lung carcinoma (NSCLC) cells to cisplatin

Perona, R., Chattopadhyay, S., Tapia, M., Rovira, A., Belda-Iniesta, C., Moratilla, C., Machado, R., Manguan, C., Cejas, P., Fresno, J., Nistal, M., De Castro, J., Albanell, J., Baron, M.

Journal:

Year:

2005

Language:

english

File:

PDF, 148 KB

english, 2005

18

Defects inmTRstability and telomerase activity produced by theDkc1A353Vmutation in dyskeratosis congenita are rescued by a peptide from the dyskerin TruB domain

Rosario Machado-Pinilla, Jaime Carrillo, Cristina Manguan-Garcia, Leandro Sastre, Alexander Mentzer, B.-W. Gu, Philip J. Mason, Rosario Perona

Journal:

Clinical and Translational Oncology

Year:

2012

Language:

english

File:

PDF, 605 KB

english, 2012

19

High resolution melting analysis for the identification of novel mutations in DKC1 and TERT genes in patients with dyskeratosis congenita

Carrillo, J., Martínez, P., Solera, J., Moratilla, C., González, A., Manguán-García, C., Aymerich, M., Canal, L., del Campo, M., Dapena, J.L., Escoda, L., García-Sagredo, J.M., Martín-Sala, S., Rives,

Journal:

Blood Cells, Molecules, and Diseases

Year:

2012

Language:

english

File:

PDF, 673 KB

english, 2012

20

Survival to genotoxic stress in the presence of chromosome instability in fission yeast

I. Sanchez-Perez, A. Peralta-Sastre, C. Manguan-Garcia, R. Perona

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 89 KB

english, 2008

21

hCCR4/CNOT complex targets DNA damage signalling pathway after genotoxic stress

I. Sanchez-Perez, C. Manguan-Garcia, M. Menacho-Marquez, J.R. Murguia, R. Perona

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 90 KB

english, 2008

22

Identification of drug-sensitive prediction genes by an epigenetic reactivation screen of cisplatin-resistant NSCLC cell lines

I. Ibanez de Caceres, C. Moratilla, M. Cortes Sempere, R. Machado-Pinilla, V. Rodriguez-Fanjul, C. Manguan, J. de Castro Carpeño, C. Belda-Iniesta C, P. Cejas, R. Perona

Journal:

European Journal of Cancer Supplements

Year:

2008

Language:

english

File:

PDF, 97 KB

english, 2008

23

485 Checkpoint kinase 1 modulates sensitivity to chemotherapy in aneuploid cell lines

I. Sanchez-Pérez, A. Peralta-Sastre, C. Manguan-Garcia, A. Gonzalez-Gutierrez, C. Belda-Iniesta, R. Perona

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 46 KB

english, 2010

24

582 Expression of GSE24.2 prevents DNA damage in X-linked dyskeratosis congenita cells

C. Manguan-Garcia, R. Machado-Pinilla, L. Sastre, A. Mentzer, B.W. Gu, L. Pintado-Berniches, P.J. Mason, R. Perona

Journal:

European Journal of Cancer Supplements

Year:

2010

Language:

english

File:

PDF, 47 KB

english, 2010

25

Development and validation of a rapid HPLC method for the quantification of GSE4 peptide in biodegradable PEI–PLGA nanoparticles

Egusquiaguirre, Susana P., Manguán-García, Cristina, Perona, Rosario, Pedraz, José Luís, Hernández, Rosa Maria, Igartua, Manuela

Journal:

Journal of Chromatography B

Year:

2014

Language:

english

File:

PDF, 613 KB

english, 2014

26

Development of surface modified biodegradable polymeric nanoparticles to deliver GSE24.2 peptide to cells: A promising approach for the treatment of defective telomerase disorders

Egusquiaguirre, Susana P., Manguán-García, Cristina, Pintado-Berninches, Laura, Iarriccio, Laura, Carbajo, Daniel, Albericio, Fernando, Royo, Miriam, Pedraz, José Luís, Hernández, Rosa M., Perona, Ros

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2015

Language:

english

File:

PDF, 2.64 MB

english, 2015

27

Mutations in XLF/NHEJ1/Cernunnos gene results in downregulation of telomerase genes expression and telomere shortening

Carrillo, Jaime, Calvete, Oriol, Pintado-Berninches, Laura, Manguan-García, Cristina, Sevilla Navarro, Julian, Arias-Salgado, Elena G., Sastre, Leandro, Guenechea, Guillermo, López Granados, Eduardo,

Journal:

Human Molecular Genetics

Year:

2017

Language:

english

File:

PDF, 1.03 MB

english, 2017

28

Expression of the Genetic Suppressor Element 24.2 (GSE24.2) Decreases DNA Damage and Oxidative Stress in X-Linked Dyskeratosis Congenita Cells

Manguan-Garcia, Cristina, Pintado-Berninches, Laura, Carrillo, Jaime, Machado-Pinilla, Rosario, Sastre, Leandro, Pérez-Quilis, Carme, Esmoris, Isabel, Gimeno, Amparo, García-Giménez, Jose Luis, Pallar

Journal:

Year:

2014

Language:

english

File:

PDF, 1.48 MB

english, 2014

29

GSE4, a Small Dyskerin- and GSE24.2-Related Peptide, Induces Telomerase Activity, Cell Proliferation and Reduces DNA Damage, Oxidative Stress and Cell Senescence in Dyskerin Mutant Cells

Iarriccio, Laura, Manguán-García, Cristina, Pintado-Berninches, Laura, Mancheño, José Miguel, Molina, Antonio, Perona, Rosario, Sastre, Leandro, Lustig, Arthur J.

Journal:

Year:

2015

Language:

english

File:

PDF, 4.54 MB

english, 2015

30

A mixed application of an objective synoptic classification and spatial regression models for deriving winter precipitation regimes in the Eastern Pyrenees

Lemus‐Canovas, Marc, Ninyerola, Miquel, Lopez‐Bustins, Joan A., Manguan, Santiago, Garcia‐Sellés, Carles

Journal:

International Journal of Climatology

Year:

2019

Language:

english

File:

PDF, 31.91 MB

english, 2019

31

Structure of Dictyostelium discoideum telomeres. Analysis of possible replication mechanisms

Rodriguez-Centeno, Javier, Manguán-García, Cristina, Perona, Rosario, Sastre, Leandro, Lustig, Arthur J.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.73 MB

english, 2019

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